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From Microbial Detection to Immune Profiling: Analytical Strategies for Fusobacterium nucleatum in Colorectal Cancer and Liver Metastasis
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马
J
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Y
G
Q
DOI：10.1016/j.trac.2026.119040.png)
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Abstract
En 中文
• Emerging analytical technologies are reviewed for Fusobacterium nucleatum detection in CRC and CRLM. • Digital PCR, CRISPR diagnostics, and NGS enable highly sensitive microbial profiling. • Multi-omics platforms reveal host–microbe interactions and immune modulation mechanisms. • Biosensors and microfluidics support rapid, decentralized, and point-of-care analysis. • Machine learning facilitates integration of microbiome, immune, and clinical datasets.
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