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Functional Autoantibodies in Myocardial Diseases
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DOI:10.1016/j.jacbts.2026.101636.png)
Abstract
En 中文
• Clinical need: Autoantibodies in myocardial diseases lack validated clinical use. • Main message: Cardiac autoantibodies show diverse, context-dependent effects. • Future directions: Validate assays, clarify causality, use high-throughput profiling.
Keywords:
autoantibodies
myocardial autoimmunity
therapeutic removal
cardio-Immunology
AAb
autoantibody
ACM
arrhythmogenic cardiomyopathy
AF
atrial fibrillation
ARVC
arrhythmogenic right ventricular cardiomyopathy
β1AR
β1-adrenergic receptor
CMyH
cardiac myosin-heavy chain
cTNI
cardiac troponin I
cTNT
cardiac troponin T
DCM
dilated cardiomyopathy
GPCR
G-protein coupled receptor
HF
heart failure
HSP
heat shock protein
LV
left ventricle
PPCM
peripartum cardiomyopathy
SARD
systemic autoimmune rheumatic disease
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