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Functional connectivity of the medial prefrontal cortex and posterior cingulate cortex mediates the association between expressive suppression and rumination in depressed adolescents
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DOI：10.1016/j.jad.2026.122328.png)
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Abstract
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• Expressive suppression was linked to all rumination measures in adolescents with MDD. • FC patterns involved prefrontal, insular, parietal, temporal, and cingulate regions. • Right mPFC–right PCC and right mPFC–left PCC FC were linked to brooding. • Findings refine neurocognitive models of brooding in adolescent MDD.
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