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FUS maintains TAZ fluidity and function

delete2024-01-03
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Wanjin Hong *
DOI:10.1038/s41556-023-01318-2delete
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Abstract

Abstract

En 中文
The transcriptional coactivators TAZ and YAP pair with transcriptional enhanced associate domains (TEADs) to regulate transcription. TAZ and YAP nuclear condensates ensure optimal transcription. A new study reports that FUS regulates TAZ condensates by maintaining them in a fluid state to drive transcription of target genes.

Journal

Nature Cell Biology cover
Nature Cell Biology
IF:
19.1
Papers:
6.1K
Citations:
4.8W

Organization

A
agency for science technology & research (a*star)
Scholars:
2.2W
Papers: 1.9W
Citations: 57