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Fusobacterium nucleatum and response to treatment in colon and rectal cancer: a systematic review
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DOI：10.1016/j.ctrv.2026.103182.png)
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Abstract
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• Higher Fusobacterium nucleatum abundance is associated with poorer treatment response in colon and rectal cancer. • In rectal cancer, persistent Fusobacterium nucleatum after neoadjuvant chemoradiotherapy correlates with increased relapse risk in rectal cancer. • Fusobacterium nucleatum may represent a predictive biomarker and potential therapeutic target in colorectal cancer.
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