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Gabija restricts phage circularization and DNA replication

delete2026-07-16
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PRE
AI
A
Alex Hong
M
Miaoxi Liu
A
Alexis Truta
A
Alexander Talaie
G
Gerald R. Smith
J
Joseph Bondy‐Denomy *
DOI:10.1016/j.chom.2026.06.016delete
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Abstract

Abstract

En 中文
• Gabija prevents phage genome circularization • Gabija limits phage and plasmid replication without host growth arrest • Exposed DNA ends and diverse phage end-binding proteins license DNA targeting by Gabija • RecBCD protects the host from Gabija, which restricts DNA devoid of RecBCD

Journal

C
Cell Host & Microbe
IF:
18.7
Papers:
98
Citations:
0

Organization

F
fred hutchinson cancer center
Scholars:
1.3K
Papers: 479
Citations: 0
D
department of microbiology & immunology
Scholars:
14
Papers: 3
Citations: 0