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Gadolinium-doped quantum dots: From synthesis to applications, surface functionalization, detection, and toxicity
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DOI：10.1016/j.dyepig.2026.113749.png)
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Abstract
En 中文
Fluorescent quantum dots (QDs) with size smaller than 10 nm have been explored as potential nanomaterials for biosensing applications because of their desirable electrochemical and photophysical properties. The high surface-to-volume ratio of these QDs allows for efficient surface functionalization with biorecognition molecules, which makes them suitable for sensitive and selective detection of biologically relevant targets. Among these, gadolinium-doped quantum dots (Gd-QDs) are of great interest because of their dual fluorescence and magnetic properties. This review article briefs about the recent advances in the synthesis methods, surface chemistry, and functionalization of Gd-QDs, especially in relation to biosensing and substrate detection of small biomolecules, microorganisms, metals, and non-metal ions. Some examples are provided to demonstrate the potential of Gd-QDs in targeted imaging and magnetic-optical biosensing. Finally, challenges and future perspectives are provided in relation to the biocompatibility and translational feasibility of Gd-QDs-based biosensors.
Keywords:
Gadolinium
Quantum dots
Gadolinium-doped quantum dots
Gd-QDs
Biosensors
Analyte detection using biosensors
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4.2
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1.3W
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2.9W
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