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Gender influence on ultrasound-assessed therapeutic response in rheumatoid arthritis: Insights from the GENder on UltraSound (GENUS) study

delete2026-05-09
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PRE
AI
J
J. Molina Collada
F
Francisco Gabriel Jiménez-Núñez
F
F. Ortiz-Márquez
P
Pablo Rodríguez-Merlos
L
Lucia Mayordomo
C
Celia Azabal-Perez
M
Minerva Berrocal-Acedo
J
Jacqueline Usón
E
Elena Garmendia
J
Javier Arostegui-Lavilla
M
María Luz García-Vivar
M
María Rosa Exposito-Molinero
J
Julio Medina-Luezas
A
Ana Corral Bote
M
Monserrat Robustillo-Villarino
A
Andrés Zúñiga-Vera
P
Paz Collado
M
María Alcalde-Villar
O
Otto Olivas-Vergara
P
Paula Estrada
DOI:10.1016/j.semarthrit.2026.152993delete
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Abstract

Abstract

En 中文
• This study is the first to show that the short-term response of ultrasound-assessed synovial inflammation to targeted therapy for RA was similar in women and men with active disease. Moreover, residual synovitis on ultrasound was similar in women and men who achieved clinical remission after targeted therapy for active RA. • Our study may provide insight into the causes of poorer therapeutic response in terms of pain and function in women, which may not be related to the response of joint synovial inflammation. This may assist in optimising targeted therapy and pain management in women with RA.
Keywords:
gender
rheumatoid arthritis
ultrasound
synovial inflammation
targeted therapy

Journal

Seminars in Arthritis and Rheumatism cover
Seminars in Arthritis and Rheumatism
IF:
4.4
Papers:
423
Citations:
1.0W

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