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Generation of iPSC-Derived White Adipose Tissue Spheroids for a Functional Adipose Model

delete2026-05-09
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PRE
AI
Ö
Özüm Begüm Böke
E
Ezgi Bulut-Okumuş
F
Fikrettin Şahin
A
Aslı Taşlıdere
A
Ayşegül Doğan*
DOI：10.1016/j.bej.2026.110241delete
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Abstract

Abstract

En 中文
• Mature white adipose tissue spheroids were generated from iPSC-derived NMPs. • WAT spheroid secretome contains EV-like particles and has high triglycerides. • WAT spheroid CM supplementation to β-TC-6 cells increased insulin secretion
Keywords:
iPSC-derived white adipose tissue
spheroids
secretome
extracellular vesicles
insulin secretion

Journal

Biochemical Engineering Journal cover
Biochemical Engineering Journal
IF:
3.8
Papers:
6.2K
Citations:
1.4W

Organization

Y
yeditepe university
Scholars:
314
Papers: 173
Citations: 0
I
inönü university
Scholars:
25
Papers: 12
Citations: 0
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