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Genome sequence of protease-free Bacillus anthracis BH500 strain created for protein production

delete2026-03-01
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PRE
AI
A
Ankur Bothra
R
Routsong, Ryan M.
P
Pomerantsev, Andrei P.
K
Kuhn, Skyler
S
Stephen H. Leppla *
DOI:10.1128/mra.00015-26delete
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Abstract

Abstract

En 中文
Bacillus strains efficiently secrete heterologous recombinant proteins as well as multiple proteases, with the latter destroying the former. Strains deleted of multiple secreted proteases are therefore preferred as protein expression hosts. We report the genome sequence of one such easily available strain, Bacillus anthracis BH500.
Keywords:
Bacillus anthracis
proteases
genomes

Journal

M
Microbiology Resource Announcements
IF:
0.6
Papers:
534
Citations:
3.1K

Organization

N
national institutes of health (nih) - usa
Scholars:
10.2W
Papers: 8.2W
Citations: 111