Genomic epidemiology of dengue virus serotype 3 lineage 3III_B.3.2 in Brazil: insights into its spread and dengue severity amid co-circulation of multiple dengue serotypes

Caroline do Nascimento Ferreira

doi:10.1016/j.lana.2026.101521

Genomic epidemiology of dengue virus serotype 3 lineage 3III_B.3.2 in Brazil: insights into its spread and dengue severity amid co-circulation of multiple dengue serotypes

2026-06-02

0

OA

AI

C

Caroline do Nascimento Ferreira

C

Carla Adriane Royer

C

Camila Confortin

N

Nelson Fernando Quallio Marques

M

Mayra Marinho Presibella

A

Aline Andrade Freund

K

Karoline Rodrigues Campos

C

Claudio Tavares Sacchi

A

Adriano Abbud

G

Gustavo Barbosa de Lima

C

Clarice Neuenschwander Lins de Morais

V

Veronica Gomes da Silva

K

Keilla Maria Paz e Silva

M

Mayara Matias de Oliveira Marques da Costa

S

Sabrina Gonçalves

S

Sofia Isabel Rótulo Araújo

D

Darcita Buerger Rovaris

E

Edson Delatorre

R

Rodrigo Ribeiro‐Rodrigues

P

Pedro Augusto Alves

DOI：10.1016/j.lana.2026.101521

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Abstract

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After over a decade of minimal circulation, DENV-3 reemerged in Brazil in 2023, driven by the newly detected lineage 3III_B.3.2. Elucidating the patterns of DENV-3 spread and impact on public health, is critically important in the context of Brazil’s hyperendemic dengue scenario. Here, we aimed to investigate the spatiotemporal dispersion of this new lineage and its epidemiological impact in Brazil.

Keywords:

DENV-3

Dengue severity

Genomic surveillance

Phylogeography

Brazil

Genomic epidemiology of dengue virus serotype 3 lineage 3III_B.3.2 in Brazil: insights into its spread and dengue severity amid co-circulation of multiple dengue serotypes

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