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Global epidemiological survey and genomic analysis of multiple carbapenemases-producing Citrobacter freundii
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DOI：10.1016/j.jgar.2026.06.010.png)
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Abstract
En 中文
• Multi-carbapenemase-producing Citrobacter freundii are distributed across multiple continents and geographic regions. • Phylogenetic analysis reveals high genetic diversity without clear geographic or clonal clustering. • Multiple plasmid replicon types co-exist within individual multi-carbapenemase-producing C. freundii isolates. • These findings identify C. freundii as an underappreciated reservoir and dissemination vector of carbapenemase genes.
Keywords:
Multiple carbapenemases resistance
Citrobacter freundii
Phylogeography
Global epidemiology
Journal
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