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Glycosylation profile of Mycobacterium leprae-specific antibodies associated with disseminated infection

delete2026-06-20
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OA
AI
A
Anouk van Hooij *
W
Wenjun Wang
C
Cristiana Santos de Macedo
J
Jan Nouta
S
Steinar Gijze
R
Roberta Olmo Pinheiro
C
Colette L.M. van Hees
M
Manfred Wuhrer
A
Annemieke Geluk
DOI：10.1016/j.isci.2026.116373delete
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Abstract

Abstract

En 中文
• Patients with disseminated leprosy induced PGL-I-specific IgM and IgG • IgG1 was the predominant subclass of M. leprae-specific PGL-I IgG • Similar IgG1 Fc glycoprofiles were detected in Dutch and Brazilian patients • PGL-I IgG1 was highly fucosylated, with lower sialylation and galactosylation
Keywords:
biological science

Journal

iScience cover
iScience
IF:
4.1
Papers:
4.6K
Citations:
4.1W

Organization

L
leiden university medical center
Scholars:
1.1K
Papers: 379
Citations: 0
E
Erasmus Medical Center
Scholars:
543
Papers: 243
Citations: 7
F
fiocruz
Scholars:
422
Papers: 135
Citations: 0
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