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Heart-Brain Axis Dysregulation in PTSD mice: Vagal-Mediated Insular Cortex Hyperactivity and Its Reversal by Propranolol
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DOI：10.1016/j.ejphar.2026.178961.png)
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Abstract
En 中文
While abnormal brain connectivity is central to PTSD, sympathetically-driven cardiac dysfunction also occurs. Given the established role of cardiac modulation of brain function and its implication in psychiatric disorders, this study aims to delineate the role of the heart-brain connection in the mechanisms underlying PTSD.
Keywords:
PTSD
heart-brain axis
vagal modulation
insular cortex
propranolol
Journal
IF:
4.7
Papers:
2.3W
Citations:
4.0W
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Cited Papers