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Heme-induced kallikrein-kinin system activation in hemolytic uremic syndrome

delete2026-08-05
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OA
AI
A
Alexandra Gerogianni
N
Niklas Friberg
M
Markus Wendler
S
Sára Kellnerová
A
Alex Antill
A
Ann‐Charlotte Kristoffersson
J
Johan Flygare
I
Ida Arvidsson
D
Diana Karpman *
DOI：10.1016/j.kint.2026.05.034delete
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Abstract

Abstract

En 中文
Heme is released from red blood cells during hemolytic uremic syndrome (HUS). Here, we investigated hemolysis-induced kallikrein-kinin system activation and the interaction between heme and clotting factor XII (FXII).
Keywords:
bradykinin
C1-inhibitor
factor XII
heme
hemolysis
hemolytic uremic syndrome
kallikrein

Journal

Kidney International cover
Kidney International
IF:
12.6
Papers:
1.6W
Citations:
4.8W

Organization

L
Lund University
Scholars:
2.0K
Papers: 859
Citations: 5.1W
Cited Papers

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