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Highly flexible antibiotic implants for root canal treatment
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DOI：10.1016/j.jconrel.2026.115221.png)
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Abstract
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• PEVA-based implants are studied as temporary infills for root canal therapy. • Ram extrusion allows precise tuning of implant diameter from 0.3 to 1.5 mm. • Gentamicin sulfate was released from the PEVA matrix over several weeks. • The implants showed antibacterial efficacy against Enterococcus faecalis in vivo. • The implant flexibility and stability are suitable for dental implantation.
Keywords:
Root canal
Antimicrobial implant
Gentamicin sulfate
PEVA
Galleria mellonella model
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