.png){kind=icon}
.png){kind=icon}
Return
How lability impacts the biological activity of polynuclear μ-oxo bridged ruthenium acetates
.png){kind=icon}
OA
AI
P
F
H
I
A
L
R
S
DOI：10.1016/j.jinorgbio.2026.113390.png)
.png){kind=icon}
.png){kind=icon}
Share.png){kind=icon}
Save
Abstract
En 中文
• The compound [Ru2O(CH3COO)2(pyridine)4(tetrahydroisoquinoline)2](PF6)2 (1) is presented. • X-ray data unraveled its molecular structure. • In aqueous and buffered media, compound 1 undergoes hydrolysis, with k ∼ 10−4 s−1. • 1 interacts moderately with HSA through dynamic quenching mechanism. • 1 is less cytotoxic to cancer cells than its inert analogue [Ru3O(CH3COO)6(THIQ)3]PF6.
Keywords:
Metallodrug
Diruthenium
Oxo-bridged compounds
5,6,7,8-tetrahydroisoquinoline
Trans effect
HSA interaction
AI Summary
Key information extracted from the uploaded paper, including a brief overview, abstract, background, key highlights, visual analysis, and future outlook.
Journal
IF:
3.2
Papers:
7.1K
Citations:
1.2W
Organization
Cited Papers