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Identifying abnormal patterns of wall shear stress in mild-to-moderate aortic dilation and tricuspid valves using permutation tests

delete2026-07-20
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OA
AI
C
Chiara Trenti *
D
Deneb Boito
F
Filip Hammaréus
J
Jennifer Suhil Habib
M
Marcus Lindenberger
E
Eva Swahn
L
Lena Jonasson
B
Bertil Wegmann
P
Petter Dyverfeldt
DOI:10.1016/j.jocmr.2026.102778delete
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Abstract

Abstract

En 中文
Aortic wall shear stress (WSS) maps allow three-dimensional visualization and quantification of WSS patterns in the aorta and can be used to identify patch-wise differences between cohorts. However, a method addressing the multiplicity of the testing should be considered when investigating patch-wise differences. In this study, we sought to explore the capability of permutation tests in addressing the regional statistical differences in WSS values between patients with mild-to-moderate aortic dilation with tricuspid valves and age- and sex- matched controls.
Keywords:
3D
three-dimensional
4D
four-dimensional
BAV
Bicuspid aortic valve
BSA
Body Surface Area
CE
contrast-enhanced
DBP
Diastolic blood pressure
FNR
False negative rate
FPR
False positive rate
MRI
Magnetic Resonance Imaging
OSI
Oscillatory Shear Index
SBP
Systolic blood pressure
PC MRA
Phase contrast MR angiography
TAV
Tricuspid aortic valve
TAWSS
Time-averaged WSS
TFCE
Threshold-free cluster enhancement
VENC
velocity encoding limit
WSS
Wall Shear Stress
Wall shear stress
4D Flow CMR
permutation tests
aortic disease

Journal

Journal of Cardiovascular Magnetic Resonance cover
Journal of Cardiovascular Magnetic Resonance
IF:
6.1
Papers:
2.3K
Citations:
6.9K

Organization

L
Linkoping University
Scholars:
1.6W
Papers: 1.5W
Citations: 184
Cited Papers

Cited Papers

Citing Papers

Citing Papers