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IFN-γ and its receptor: the roles of antiviral and antibacterial immunity in black rockfish Sebastes schlegelii
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DOI：10.1016/j.fsi.2026.111644.png)
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Abstract
En 中文
• SsIFN-γ mediates antigen presentation, IL-17 signaling and cell apoptosis. • SsIFN-γ directly binds both receptor subunits SsIFNGR1 and SsIFNGR2. • SsIFNGR1/2 could enhance SsIFN-γ-mediated antiviral activity in vitro. • SsIFNGR1/2 alleviate E. piscicida-induced intestinal damage in vivo. • SsIFNGR1/2 activate JAK-STAT signaling and pro-inflammatory cytokines in vitro/vivo.
Keywords:
Sebastes schlegelii
IFN-γ receptor
Transcriptomics
Signal transduction
Antiviral immunity
Antibacterial immunity
Journal
F
IF:
3.9
Papers:
367
Citations:
0