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Impact of Alcohol on Gut Microbial Metabolism and the Gut-Liver-Brain Axis

delete2026-05-05
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PRE
AI
L
Linton Freund
B
Berenice Ramirez Leal
C
Cynthia L. Hsu *
DOI:10.1016/j.alcohol.2026.04.009delete
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Abstract

Abstract

En 中文
• Alcohol drives dysbiosis and disrupts key gut microbial functions • Reduced SCFA production weakens gut and brain barriers, promoting systemic disease • Alcohol promotes ethanol-producing Proteobacteria that drive liver injury • Alcohol-driven Fusobacterium expansion strengthens biofilms and promotes GI cancer • Targeting disrupted microbial functions may improve alcohol-related outcomes
Keywords:
Alcohol
Gut Microbiota
Dysbiosis
SCFA
Gut-Liver-Brain Axis

Journal

Alcohol cover
Alcohol
IF:
2.9
Papers:
192
Citations:
3.1K

Organization

U
university of california san diego
Scholars:
4.6K
Papers: 2.1K
Citations: 1
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