.png){kind=icon}
.png){kind=icon}
Return
Impact of preoperative cannabis use on short and mid-term postoperative outcomes following total hip and knee arthroplasty
.png){kind=icon}
PRE
AI
Z
L
A
J
J
Z
DOI：10.1016/j.jor.2025.12.006.png)
.png){kind=icon}
Original request for help.png){kind=icon}
Share.png){kind=icon}
Save
Abstract
En 中文
Introduction: With legal recreational cannabis use rising, its impact on postoperative outcomes after total hip (THA) and knee arthroplasty (TKA) remains unclear. This study evaluates whether preoperative cannabis use is associated with postoperative complications, healthcare utilization, and implant-related failure. Methods: A retrospective cohort study was conducted using a national database on patients undergoing primary THA or TKA. Cannabis users were 1:1 propensity-matched to non-users, resulting in 1504 THA and 1354 TKA patients per group. Outcomes included 90-day emergency department (ED) visits, hospitalizations, opioid use, and 2-year orthopaedic complications (aseptic loosening, infection, dislocation, revision). Bivariate comparisons assessed statistical significance. Results: Cannabis use was linked to increased 90-day ED visits and opioid use. In THA, ED visits were 16.1 % vs 12.6 % (p = 0.006), opioid use was 91.8 % vs 86.4 % (p < 0.001). In TKA, ED visits were 13.1 % vs 9.9 % (p = 0.008), opioid use was 92.8 % vs 88.6 % (p < 0.001). Hospitalization and major complications were similar. At 2 years, THA patients with cannabis use had higher rates of aseptic loosening (1.9 % vs 0.9 %, p = 0.030). Other THA complications - joint infection (4.4 % vs 4.6 %, p = 0.724), dislocation (3.4 % vs 2.6 %, p = 0.162), revision (6.2 % vs 7.1 %, p = 0.340) - were not significantly different. Among TKA patients, rates of aseptic loosening (1.0 % vs <0.7 %, p = 0.530), infection (4.9 % vs 3.8 %, p = 0.160), dislocation (<0.7 % vs 0.9 %, p = 0.669), and revision (5.3 % vs 5.2 %, p = 0.932) showed no significant differences. Conclusions: Preoperative cannabis use is associated with increased ED visits and opioid use at 90 days, and higher rates of aseptic loosening after THA at 2 years. These findings suggest a need for further research and preoperative counseling on cannabis use in arthroplasty patients.
Keywords:
OPIOID USE
MARIJUANA
Journal
J
IF:
1.5
Papers:
239
Citations:
3.2K
Organization
Cited Papers