1
Return

Implanted Dynamic Electric Field Therapy for Glioblastoma: Preclinical Safety and Efficacy of Intratumoral Modulation Therapy

delete2026-06-11
delete0
delete
OA
AI
E
Erin Iredale *
N
Niveen Fulcher
A
Amir H Akbarzadeh
A
Abdulla Elsaleh
E
Elizabeth Fenton
C
Cleusa De Oliveira
J
John A Ronald
J
John J Kelly
S
Susanne Schmid
T
Terry M Peters
E
Eugene Wong
M
Matthew O Hebb
DOI：10.1093/noajnl/vdag160delete
deleteOriginal
deleteOriginal request for help
deleteShare
deleteSave
Abstract

Abstract

En 中文
Electric field-based approaches show therapeutic impact against glioblastoma, with 1–3 V/cm often cited as the range of threshold intensities for antitumor effects. However, the field amplitudes required for maximal impact, and strategies needed to achieve them in the brain remain poorly defined. This study aimed to evaluate the safety, electrical integrity, field distribution, and efficacy of a novel implanted Intratumoral Modulation Therapy (IMT) delivering spatiotemporally dynamic electric fields in an aggressive in vivo glioblastoma model.

Journal

N
Neuro-Oncology Advances
IF:
4.1
Papers:
1.5K
Citations:
3.2K

Organization

H
hannover medical school
Scholars:
2.7K
Papers: 1.1K
Citations: 0
W
western university
Scholars:
1.1K
Papers: 576
Citations: 0
Cited Papers

Cited Papers

Citing Papers

Citing Papers