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Improving reirradiation of recurrent non-small cell lung cancer through non-coplanar beam arrangements
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DOI：10.1016/j.phro.2025.100874.png)
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Abstract
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• Simultaneous optimization of cumulative EQD2 distribution and non-coplanar arcs. • Non-coplanar arcs enhance OAR sparing in NSCLC reirradiation vs coplanar arcs. • Maximum cumulative EQD2 reduced by up to 9 Gy for key thoracic OARs. • ≥5 Gy cumulative EQD2 reduction achieved for dose-limiting OARs in 40 % of patients.
Keywords:
Reirradiation
Beam orientation optimization
Non-coplanar radiotherapy
Non-small cell lung cancer
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