Incidence and Prevalence of Syphilitic Uveitis and Associated Ocular Complications in the TriNetX Database

Lucy R. Zhou

doi:10.1016/j.ajo.2025.05.048

Incidence and Prevalence of Syphilitic Uveitis and Associated Ocular Complications in the TriNetX Database

2025-06-04

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DOI：10.1016/j.ajo.2025.05.048

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• Positive treponemal and non-treponemal tests identified cases of syphilitic uveitis in the TriNetX database. • The cumulative incidence and prevalence from 2013-2024 were 0.36 and 0.27 per 100,000, respectively. • HIV co-infection occurred in 32.49% and 27.85% had low vision or blindness. • A timely diagnosis and intravenous penicillin can prevent irreversible visual complications.

Incidence and Prevalence of Syphilitic Uveitis and Associated Ocular Complications in the TriNetX Database

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