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Inferior turbinate reduction for refractory pediatric allergic rhinitis: Symptom control and sleep-related quality of life outcomes
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DOI：10.1016/j.amjoto.2026.104813.png)
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Abstract
En 中文
Objective: To compare symptom control, sinonasal and sleep-related quality of life in children with refractory allergic rhinitis treated with inferior turbinate reduction versus medical therapy. Design: This is a prospective cohort pilot study. Population: Children aged 5-17 years with a documented allergic rhinitis refractory to 3 months of medical therapy, were recruited. The study group consisted of children who underwent surgery and the control group included children who remained on medical therapy. Primary outcomes: Three questionnaires pertaining to the sinus and nasal quality of life (SN-5), obstructive sleep apnea symptoms (OSA-18), and nasal obstruction symptom evaluation (NOSE) were collected before and after intervention at 1 and 3 months. Flexible endoscopic findings of disease regression before and after intervention were also mentioned. Results: Thirty-four subjects were recruited, 17 of whom underwent surgery and 17 who received medical therapy. At 1 month follow-up, the mean drop in the questionnaires' scores (SN-5; OSA-18; NOSE) was greater in the study group (9.9 +/- 5.8; 23.2 +/- 9.8, 8.2 +/- 3.8, respectively) compared to the control group (6.8 +/- 3.9, 17.3 +/- 7.1, 4.6 +/- 2.8, respectively). The difference in symptoms improvement between the two groups was a statistically significant in all three questionnaires (p = 0.029; p = 0.037; p = 0.005; respectively). Similar results were obtained at 3 months follow-up. Almost all patients in the surgery group (88.2%) had complete disease regression in comparison to only 29.4% in the control group (p < 0.001). Conclusion: Introducing surgery to children with refractory allergic rhinitis can significantly improve the patient's symptoms and quality of life.
Keywords:
Allergic rhinitis
Nasal obstruction
Turbinate reduction
Rhinology
Pediatric otolaryngology
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