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Inflammation Hinders Anabolic Potential of Nutritional Support in Cancer: Findings from the PRIMe trial
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DOI：10.1016/j.ajcnut.2026.101467.png)
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Abstract
En 中文
Our recent PRIMe trial suggested that increasing daily protein intake via nutrition counseling in patients with colorectal cancer positively impacts muscle mass.
Keywords:
cancer
cytokines
IL-6
amino acids
anabolic responsiveness
protein supplementation
body composition
lean soft tissue
AA
Amino acids
ALST(I)
appendicular lean soft tissue (index)
BCAA
branched-chain amino acid
BMI
body mass index
CRP
C-reactive protein
DXA
Dual energy X-ray absorptiometry
EAA
Essential amino acids
FFM
fat-free mass
FM
fat mass
HP
high protein
IL
interleukin
LST
lean soft tissue
NEAA
non-essential amino acids
NP
normal protein
PC
partial correlation
PRIMe
Protein Recommendation to Increase Muscle
QoL
quality of life
SGA
Subject global assessment
SPPB
short physical performance battery
Sum AA
Sum all measured amino acids
TNF
tumor necrosis factor
VAT
visceral adipose tissue
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