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Innovative Algorithm for Keratoconus Intelligent Grading Using Variational Encoding Bayesian Gaussian Mixture Model

delete2026-01-23
delete0
PRE
AI
Z
Zuoping Tan
X
Xuan Chen
S
Shuangcheng Li
L
Lijuan Yue
T
Tinghui Huang
R
Rui Yao
J
Jianying Lv
J
Jing Li
C
Caiye Fan
R
Riwei Wang
Y
Yuanyuan Wang *
王
王艳 (Yan Wang) *
DOI:10.1016/j.bspc.2026.109642delete
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Abstract

Abstract

En 中文
The variational encoding Bayesian Gaussian mixture model is a novel unsupervised machine learning model that combines variational encoding and Bayesian inference. The model uses a variational encoder to learn the continuous, structured latent space of a dataset and combines multiple Gaussian mixture distributions, offering robust learning and generalisation capabilities. Although it is well-suited for modelling complex relationships, this model has not yet been explored in grading keratoconus, a blinding eye disease with unclear etiology or standardised diagnostic treatment systems. Therefore, this study applies the Bayesian Gaussian mixture model to categorise keratoconus severity and identifies relatively sensitive features for early diagnoses and interventions, potentially improving clinical decision-making and visual outcomes.

Journal

Biomedical Signal Processing and Control cover
Biomedical Signal Processing and Control
IF:
4.9
Papers:
1.0W
Citations:
2.4W

Organization

X
Xi'an People's Hospital
Scholars:
41
Papers: 24
Citations: 0
W
Wenzhou University of Technology
Scholars:
476
Papers: 455
Citations: 367
N
nankai university
Scholars:
4.8W
Papers: 3.3W
Citations: 74
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Cited Papers

Cited Papers

Combined biomechanical and tomographic keratoconus staging: Adding a biomechanical parameter to the ABCD keratoconus staging system
err2021-10-16
err37
errOAAI
errFlockerzi, Elias; Vinciguerra, Riccardo; Belin, Michael Wellington; Vinciguerra, Paolo; Ambrosio Jr, Renato; Seitz, Berthold
errShare
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Unsupervised Gaussian Mixture-Model With Expectation Maximization for Detecting Glaucomatous Progression in Standard Automated Perimetry Visual Fields
err2016-05-03
err0
errOAAI
errSiamak Yousefi; Madhusudhanan Balasubramanian; Michael H. Goldbaum; Felipe A. Medeiros; Linda M. Zangwill; Robert N. Weinreb; Jeffrey M. Liebmann; Christopher A. Girkin; Christopher Bowd
errShare
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Correlation of the Corvis Biomechanical Factor with tomographic parameters in keratoconus
err2022-02-01
err0
PREAI
errElias Flockerzi; Riccardo Vinciguerra; Michael Wellington Belin; Paolo Vinciguerra; Renato Ambrósio; Berthold Seitz
errShare
errSave
Bayesian networks in healthcare: Distribution by medical condition
err2020-07-01
err103
errOAAI
errMcLachlan, Scott; Dube, Kudakwashe; Hitman, Graham A.; Fenton, Norman E.; Kyrimi, Evangelia
errShare
errSave
Unsupervised learning for large-scale corneal topography clustering
err2020-10-12
err13
errOAAI
errZeboulon, Pierre; Debellemaniere, Guillaume; Gatinel, Damien
errShare
errSave
The Prevalence and Risk Factors for Keratoconus: A Systematic Review and Meta-Analysis
err2019-09-06
err0
PREAI
errHassan Hashemi; Samira Heydarian; Elham Hooshmand; Mohammad Saatchi; Abbasali Yekta; Mohamadreza Aghamirsalim; Mehrnaz Valadkhan; Mehdi Mortazavi; Alireza Hashemi; Mehdi Khabazkhoob
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