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Integrative metabolomic and proteomic analysis of diabetic kidney disease progression with younger-onset type 2 diabetes

delete2025-09-18
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PRE
AI
R
Resham L Gurung
H
Huili Zheng
J
Jia Le Ivan Tan BSc
S
Sylvia Liu
C
Clara C. Chan
K
Keven Ang
C
Clara Tan
J
Jianjun Liu
T
Tavintharan Subramaniam
C
Chee Fang Sum
S
Su Chi Lim *
DOI：10.1111/dom.70153delete
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Abstract

Abstract

En 中文
Younger-onset type 2 diabetes (YT2D) confers a disproportionately high risk of diabetic kidney disease (DKD), yet early biomarkers and underlying mechanisms remain poorly defined. We aimed to identify metabolites associated with DKD progression and integrate metabolomic and proteomic data to elucidate pathways involved in a multi-ethnic Asian cohort.
Keywords:
diabetes kidney disease
metabolomics
younger onset of type 2 diabetes

Journal

D
Diabetes Obesity and Metabolism
IF:
5.7
Papers:
6.1K
Citations:
1.7W

Organization

Khoo Teck Puat Hospital cover
Khoo Teck Puat Hospital
Scholars:
98
Papers: 45
Citations: 523
A
admiralty medical centre
Scholars:
5
Papers: 4
Citations: 0
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