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Intensification of reaction-extraction coupling in a rotor-stator submerged rotating packed bed reactor: Biphasic fructose dehydration to 5-hydroxymethylfurfural
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DOI：10.1016/j.ces.2026.124461.png)
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Abstract
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• RS-SRPB was developed to intensify HCl-catalyzed fructose dehydration to 5-HMF. • 5-HMF yield of 90.98% were achieved within 69.5 s at a high CFru of 1.0 mol/L. • A STY of 5.89 kg/(L·h) was obtained, two orders of magnitude higher than in stirred tank reactors. • ANN-based predictive model was developed with deviations less than ± 15%. • RS-SRPB offered a promising solution for the intensification of reaction-extraction coupling processes.
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