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Inter and intraspecific variation in Micrurus venoms from Bahia, Brazil and challenges for antivenom efficacy
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DOI：10.1016/j.biochi.2026.03.007.png)
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Abstract
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• Marked inter- and intraspecific variation in Micrurus venoms from Bahia. • Three venom phenotypes identified based on geography and taxonomy. • Proteomic profiles reveal PLA2-and 3FTx-dominant venom compositions. • Antivenom neutralized PLA2-rich venoms but failed against 3FTx-rich ones. • Findings highlight evolutionary plasticity and therapeutic implications.
Keywords:
Micrurus ibiboboca
Micrurus bonita
Coral snake
Venom variation
Venomics
Toxicity
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