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Introducing Enzyme Immobilization and Flow Biocatalysis to the Undergraduate Curriculum

delete2026-07-10
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OA
AI
P
Pablo Díaz‐Kruik
C
Calvin Klein
F
Francesca Paradisi *
DOI:10.1021/acs.jchemed.5c00681delete
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Abstract

Abstract

En 中文
An undergraduate flow biocatalysis laboratory practical experiment was developed to introduce to the students the basics of enzyme characterization, enzyme immobilization, and continuous flow processes, from a practical approach. The practical was structured in two parts─enzyme immobilization and flow biocatalysis─and intended to be executed over 4 afternoons. Within this practical, the students were able to expand and solidify their knowledge on concepts such as homogeneous and heterogeneous catalysis, flow setups vs batch reactions in a practical manner with dynamic exchanges with teaching assistants. Student performance was evaluated through a written report aligned with the main components of the practical course and mapped to specific learning objectives.
Keywords:
Biocatalysis
Immobilization
Peptides and proteins
Students
Teaching and learning methods
Upper-Division Undergraduate
Laboratory Instruction
Hands-On Learning
Laboratory Equipment
Enzymes
flow chemistry
flow biocatalysis

Journal

Journal of Chemical Education cover
Journal of Chemical Education
IF:
2.9
Papers:
1.2K
Citations:
2.3W

Organization

U
University of Bern
Scholars:
3.9W
Papers: 3.1W
Citations: 4.8W
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