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Inverse association between PFAS mixtures and body roundness index: A competitive mediation of free triiodothyronine

delete2026-07-25
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OA
AI
C
Changzi Wu
D
Dongyue Miao
D
Duo Wang
F
Feier Chen
Z
Zheng Wu
C
Chunyang Dong
张江华 cover
张江华 (Jianghua Zhang)
X
Xianbiao Shen *
T
Tian Chen *
DOI:10.1016/j.hazadv.2026.101432delete
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Abstract

Abstract

En 中文
• First study on individual and mixed PFAS exposure with body roundness index. • PFAS mixtures show significant inverse association with body roundness index. • FT3 demonstrates competitive mediation in PFAS-body roundness association. • Stronger inverse associations found in smokers and metabolic disease patients. • Nonlinear relationships detected for all PFAS with body roundness index.
Keywords:
PFAS
Body roundness index
Thyroid hormone
Cross-sectional analysis
NHANES

Journal

Journal of Hazardous Materials Advances cover
Journal of Hazardous Materials Advances
IF:
7.7
Papers:
1.4K
Citations:
3.1K

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