Investigating the Impact of Carboxylated Polystyrene Nanoplastics in the Liver Using Cell Lines and Precision-Cut Liver Slices

2026-06-14

Namrata Pandey

Paula Boeira

Nathaniel J. Clark

Eleanor T. Walker

Somaiah Aroori

Jemimah Denson

Richard C. Thompson

Matthew E. Cramp

Shilpa Chokshi

Ashwin Dhanda *

DOI：10.1111/liv.70748

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Increasing reports of plastic accumulation in human tissue have raised concerns about potential adverse health outcomes. Evidence of negative effects of nanoplastics is heterogeneous and provides limited insights into the underlying pathogenic toxicity mechanisms in humans.

Keywords:

hepatic cell lines

hepatotoxicity

human-precision cut liver slices

nanoplastic

polystyrene

Investigating the Impact of Carboxylated Polystyrene Nanoplastics in the Liver Using Cell Lines and Precision-Cut Liver Slices

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