.png){kind=icon}
.png){kind=icon}
Return
Iron-ing out ferroptosis-mediated T cell dysfunction in cancer
.png){kind=icon}
PRE
AI
E
P
DOI：10.1038/s43018-026-01204-4.png)
.png){kind=icon}
Original request for help.png){kind=icon}
Share.png){kind=icon}
Save
Abstract
En 中文
T cell dysfunction restrains the efficacy of immune checkpoint blockade and CAR-T cell-based cancer therapies. Iron-mediated ferroptosis is now shown to contribute to the dysfunction of endogenous T cells and CAR-T cells, suggesting that inhibition of ferroptosis could improve the anti-tumor activity of CAR-T cells in cancer.