.png){kind=icon}
.png){kind=icon}
Return
ISN International Expert Forum: Exploring the Nexus of Cardiovascular-Kidney-Metabolic (CKM) Health
.png){kind=icon}
PRE
AI
R
D
M
B
M
S
L
S
S
J
J
T
C
M
A
I
S
M
W
H
DOI：10.1016/j.kint.2026.06.044.png)
.png){kind=icon}
Original request for help.png){kind=icon}
Share.png){kind=icon}
Save
Abstract
En 中文
The Cardiovascular-Kidney-Metabolic (CKM) framework recognizes the interconnected biological, clinical, and societal drivers of cardiovascular disease, chronic kidney disease, diabetes, and obesity. To advance an integrated perspective, aligned with the kidney community focus, the International Society of Nephrology (ISN) convened an International Expert Forum bringing together a global and multidisciplinary team of leaders in this field. This meeting report synthesizes key discussions spanning CKM risk stratification, lifestyle interventions, guideline-directed medical therapies, emerging late-stage therapeutics, and models of care delivery. Participants emphasized the importance of early, integrated case-finding; long-term, joint kidney–cardiovascular risk assessment; and timely use of evidence-informed therapies to reduce kidney disease progression, kidney failure, and cardiovascular events. Persistent gaps including therapeutic inertia, fragmented care, and global inequities in access to care were highlighted, alongside promising multidisciplinary and system-level care models. Emerging therapies targeting residual risk further underscore the need for adaptive implementation strategies. Aligned with ISN’s mission, this forum represents a foundational step toward connecting disciplines, bridging evidence-to-practice gaps, and building global capacity to improve equitable CKM outcomes.
Journal
IF:
12.6
Papers:
1.6W
Citations:
4.8W
Organization
No organization information available
Cited Papers