1
Return

Isoprothiolane impairs heart and vascular development in zebrafish embryos through inhibition of Wnt signaling pathway

delete2026-05-09
delete0
PRE
AI
N
Nan Yin
L
Lirong Huang
Y
Yunlong Meng
W
Wenwen Zha
H
Haining Li
K
Kangyu Liu
Y
Yuanhai Xie
Z
Zilin Zhong *
陈建军 cover
陈建军 (Jianjun Chen) *
DOI：10.1016/j.jes.2026.05.021delete
deleteOriginal
deleteOriginal request for help
deleteShare
deleteSave
Abstract

Abstract

En 中文
• Isoprothiolane exposure can affect early embryogenesis in zebrafish. • Isoprothiolane impairs cardiovascular development. • Transcriptomics revealed isoprothiolane inhibited Wnt signaling pathway. • BML-284 partially rescues isoprothiolane-induced developmental dysfunction.
Keywords:
Isoprothiolane
zebrafish embryos
cardiovascular development
Wnt signaling pathway
transcriptomics

Journal

Journal of Environmental Sciences cover
Journal of Environmental Sciences
IF:
6.3
Papers:
7.5K
Citations:
2.4W

Organization

T
tongji university
Scholars:
7.5W
Papers: 5.8W
Citations: 98
Cited Papers

Cited Papers

Citing Papers

Citing Papers