.png){kind=icon}
.png){kind=icon}
Return
ITGA11 Regulates Lens Epithelial-Mesenchymal Transition by Modulating PTGS2-Mediated Lipid Metabolism
.png){kind=icon}
PRE
AI
X
C
Z
Y
Z
Y
Z
DOI：10.1016/j.exer.2026.111042.png)
.png){kind=icon}
Original request for help.png){kind=icon}
Share.png){kind=icon}
Save
Abstract
En 中文
• ITGA11 promotes lens epithelial-mesenchymal transition via the PTGS2 axis. • ITGA11 depletion prevents metabolic reprogramming and inflammatory signaling. • Lipidomics reveals a PTGS2-mediated arachidonic acid-to-prostaglandin shift during lens EMT. • Pharmacological inhibition of PTGS2 effectively reverses the fibrotic phenotype.
Keywords:
ITGA11
lens epithelial-mesenchymal transition
PTGS2
lipid metabolism
fibrosis
Journal
IF:
2.7
Papers:
7.6K
Citations:
1.6W
Organization
Cited Papers