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Ketogenic diet therapy in pyruvate dehydrogenase deficiency: Global clinical practice from literature and survey data
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DOI：10.1016/j.ymgme.2026.110190.png)
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Abstract
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• Ketogenic diet is a widely used and generally well tolerated therapy for patients with Pyruvate dehydrogenase deficiency. • Ketogenic diet is recommended regardless of age, genotype, or seizure status. • Benefits beyond seizure control include improved development, function and cognition.
Keywords:
Ketogenic diet therapy
Pyruvate dehydrogenase deficiency
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