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Kinase Inhibitor Cardiotoxicity Database (KICDB): a causality-oriented multi-omics database for kinase inhibitor-induced cardiotoxicity
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J
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J
DOI：10.1111/bph.70599.png)
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Abstract
En 中文
Kinase inhibitors (KIs) are essential in targeted cancer therapy but frequently cause cardiotoxicity, limiting their clinical utility. A systematic resource to explore the underlying causal mechanisms is urgently needed.
Keywords:
cardiotoxicity
drug-induced toxicity
Mendelian randomization
transcriptomics meta-analysis
tyrosine kinase inhibitors
Journal
IF:
7.7
Papers:
1.4W
Citations:
3.7W
Organization
Cited Papers