L-Theanine Activates the mTOR Signaling Pathway through TAS1R1-FRMD6 To Promote Milk Synthesis in Bovine Mammary Epithelial Cells

Xiechen Zhou

doi:10.1016/j.jnutbio.2026.110395

L-Theanine Activates the mTOR Signaling Pathway through TAS1R1-FRMD6 To Promote Milk Synthesis in Bovine Mammary Epithelial Cells

2026-05-05

0

PRE

AI

X

Xiechen Zhou

M

Mingyang Sun

N

Naiyuan Jiang

J

Ji Cheng

F

Feng Li

J

Jiaxin Wang

W

Wenjin Guo

J

Juxiong Liu

Y

Yu Cao *

S

Shoupeng Fu *

DOI：10.1016/j.jnutbio.2026.110395

Original

Original request for help

Save

Abstract

En 中文

• L-Theanine regulates the synthesis of milk in BMECs via TAS1R1. • L-Theanine can regulate the protein expression levels of FRMD6 through TAS1R1 to promote milk synthesis in BMECs. • L-Theanine can enhance the interaction between FRMD6 and mTOR, promote the translocation of mTOR from the cytoplasm to the lysosomal surface, and then activate the mTORC1 signaling pathway to promote milk synthesis.

Keywords:

L-Theanine

TAS1R1

FRMD6

mTOR signaling pathway

milk synthesis

L-Theanine Activates the mTOR Signaling Pathway through TAS1R1-FRMD6 To Promote Milk Synthesis in Bovine Mammary Epithelial Cells

Abstract

Journal

Organization