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Latent space arc therapy optimization

delete2021-11-03
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OA
AI
N
Noah Bice *
M
Mohamad Fakhreddine
R
Ruiqi Li
D
Dan Nguyen
C
Christopher Kabat
P
Pamela Myers
N
Niko Papanikolaou
N
Neil Kirby
DOI:10.1088/1361-6560/ac1b1cdelete
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Abstract

Abstract

En 中文
Volumetric modulated arc therapy planning is a challenging problem in high-dimensional, non-convex optimization. Traditionally, heuristics such as fluence-map-optimization-informed segment initialization use locally optimal solutions to begin the search of the full arc therapy plan space from a reasonable starting point. These routines facilitate arc therapy optimization such that clinically satisfactory radiation treatment plans can be created in a reasonable time frame. However, current optimization algorithms favor solutions near their initialization point and are slower than necessary due to plan overparameterization. In this work, arc therapy overparameterization is addressed by reducing the effective dimension of treatment plans with unsupervised deep learning. An optimization engine is then built based on low-dimensional arc representations which facilitates faster planning times.
Keywords:
deep learning
optimization
VMAT

Journal

Physics in Medicine and Biology cover
Physics in Medicine and Biology
IF:
3.4
Papers:
1.4W
Citations:
3.1W

Organization

U
university of texas health science center at san antonio
Scholars:
8.9K
Papers: 6.6K
Citations: 14
U
university of texas system
Scholars:
18.5W
Papers: 15.6W
Citations: 210
Cited Papers

Cited Papers

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errSCIENCE
IF45.8
err1983-05-13
err3.2W
PREAI
errKIRKPATRICK, S; GELATT, CD; VECCHI, MP
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