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Lateral hypothalamic area: A central node for maternal behavior modulation

delete2026-08-31
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A
Allan dos Anjos-Monteiro
V
Victor Hugo dos Santos-Affonso
A
Ammir Yacoub Helou
J
Jackson Cioni Bittencourt *
DOI:10.1016/j.yfrne.2026.101283delete
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Abstract

Abstract

En 中文
• The LHA acts as a central hub integrating maternal, metabolic, and motivational signals. • Distinct LHA neuropeptidergic populations differentially modulate maternal behavior. • Oxytocin-sensitive MCH neurons emerge as key regulators of parental care circuits. • Sex-biased transcriptomic programs reveal previously unrecognized LHA heterogeneity. • Single-cell approaches uncover candidate maternal-related neuronal populations in the LHA.
Keywords:
Lateral hypothalamic area
Maternal behavior
Melanin-concentrating hormone
Orexin
Oxytocin
Neuroendocrinology
Lactation
Single-cell RNA sequencing
Hypothalamus
Maternal brain
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Journal

Frontiers in Neuroendocrinology cover
Frontiers in Neuroendocrinology
IF:
6.7
Papers:
1.2K
Citations:
5.5K

Organization

U
Universidade Federal do ABC
Scholars:
158
Papers: 84
Citations: 3.3K
U
university of são paulo
Scholars:
2.5K
Papers: 828
Citations: 0
U
universidade de sao paulo
Scholars:
10.6W
Papers: 6.7W
Citations: 93
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