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Lifespan Exposure to Hormone Therapies and Structural Brain Morphometry in Older Women

delete2026-05-02
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OA
AI
R
Robyn A. Honea *
A
Amber Watts
S
Shannon D. Donofry
C
Cristina Molina-Hidalgo
H
Hayley S Ripperger
S
Sarah L. Aghjayan
C
Chaeryon Kang
S
Swathi Gujral
L
Lauren E. Oberlin
G
George Grove
H
Haiqing Huang
B
Bradley P. Sutton
J
Jeffrey M. Burns
E
Eric D. Vidoni
A
Arthur F. Kramer
E
Edward McAuley
C
Charles H. Hillman
A
Anna L. Marsland
M
M. Ilyas Kamboh
K
Kirk I. Erickson
DOI:10.1016/j.neuroimage.2026.121974delete
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Abstract

Abstract

En 中文
• Estrogen from birth control & late menopause boosts brain volume in aging/AD-prone areas. • Birth control + MHT use enhances parietal/temporal brain structure in older women. • Study links hormone timing to neuroanatomy using whole-brain morphometry. • Findings support timed estrogens exposure for AD prevention strategies.
Keywords:
estrogen
brain aging
menopause
neuroimaging
women
hormone therapy
protection
aging
brain volume
brain thickness
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NeuroImage cover
NeuroImage
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adventhealth research institute
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RAND
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university of illinois urbana-champaign
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university of pittsburgh
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