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Lipids and abdominal aortic aneurysm: from pathophysiology to therapy. A call to action from SISA and SIAPAV
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DOI：10.1016/j.numecd.2026.104856.png)
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Abstract
En 中文
• Lipid dysregulation is central to AAA pathophysiology. • LDL-cholesterol, triglycerides and Lp(a) show causal links with AAA risk. • HDL dysfunction contributes to vascular inflammation and matrix damage. • PCSK9, ANGPTL3, and apoC-III are emerging therapeutic targets. • Dedicated trials are needed to test lipid-targeted AAA therapies.
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