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Lipoprotein(a), Family History, and Incidence of Premature ASCVD Events in a Pooled US Cohort
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DOI：10.1016/j.ajpc.2025.101319.png)
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Abstract
En 中文
Lipoprotein(a) [Lp(a)] is an independent, genetic, and causal risk factor for atherosclerotic cardiovascular disease (ASCVD). There are limited data on its impact on premature ASCVD, including in diverse populations and with family history. We examined Lp(a) in relation to premature ASCVD (male aged <55, female aged <65 years) compared to later onset ASCVD, and differences by family history, sex, and race/ethnicity in a large, multi-ethnic U.S. cohort.
Keywords:
lipoprotein(a)
family history
atherosclerotic cardiovascular disease
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