Liquid biopsy miRNA risk score in bladder cancer: translational insights from patient-derived xenografts to prognostic stratification

M. Papadimitriou

doi:10.1016/j.ejca.2026.116987

Liquid biopsy miRNA risk score in bladder cancer: translational insights from patient-derived xenografts to prognostic stratification

2026-08-09

0

OA

AI

M

M. Papadimitriou

K

Katerina‐Marina Pilala

K

Konstantina Panoutsopoulou

K

Konstantinos Soureas

G

Georgios‐Christos Giagkos

P

Panagiotis Levis

Z

Zoi Kanaki

G

Gedeon Loules

Μ

Μαρία Ζαμανάκου

K

Konstantinos Stravodimos

A

Apostolos Klinakis

M

Margaritis Avgeris *

A

Andreas Scorilas

DOI：10.1016/j.ejca.2026.116987

Original

Original request for help

Save

Abstract

En 中文

• PDX-guided profiling reveals bladder cancer-specific circulating miRNAs • PDX-to-patient validation links circulating miRNAs with BlCa progression • Liquid biopsy miRNA risk-scores improve prognostic stratification • miRisk scores improve risk-stratification beyond established clinical markers • Liquid biopsy miRNA signatures support non-invasive BlCa management

Keywords:

liquid biopsy

circulating miRNAs

miRNAs

non-coding RNAs

miRNA-seq

patient-derived xenografts

PDXs

miRNA-risk score

tumor markers

circulating tumor markers

Liquid biopsy miRNA risk score in bladder cancer: translational insights from patient-derived xenografts to prognostic stratification

Abstract

Journal

Organization