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Longevity leap: mind the healthspan gap
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DOI：10.1038/s41536-021-00169-5.png)
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Abstract
En 中文
Life expectancy has increased by three decades since the mid-twentieth century. Parallel healthspan expansion has however not followed, largely impeded by the pandemic of chronic diseases afflicting a growing older population. The lag in quality of life is a recognized challenge that calls for prioritization of disease-free longevity. Contemporary communal, clinical and research trends aspiring to extend the health horizon are here outlined in the context of an evolving epidemiology. A shared action integrating public and societal endeavors with emerging interventions that target age-related multimorbidity and frailty is needed. A multidimensional buildout of a curative perspective, boosted by modern anti-senescent and regenerative technology with augmented decision making, would require dedicated resources and cost-effective validation to responsibly bridge the healthspan-lifespan gap for a future of equitable global wellbeing.
Keywords:
STEM-CELL THERAPY
REGENERATIVE MEDICINE
CARDIOVASCULAR-DISEASE
PERSONALIZED MEDICINE
OLDER-ADULTS
CANCER
CHALLENGES
TRANSPLANTATION
PREVENTION
BEHAVIORS