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Longitudinal analysis of tyrosine kinase inhibitor therapy outcomes and BCR-ABL1 transcript decline velocity in chronic myeloid leukemia: A 16-year real-world study

delete2026-08-11
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OA
AI
M
Moaath K. Mustafa Ali MD, MPH *
E
Emily C. Zabor DrPH
K
Kamilla Abdurakhmanov MS
H
Hadil Zureigat
A
Ahmed N. Mohamed MD
M
Muaz Alsabbagh Alchirazi MD
A
Aastha Dhakal MD
A
Ali Mushtaq MD
N
Naveen Rehman
A
Ameed Bawwab MD
B
Bryan Berube MD
L
Lana Khatib MD
A
Akriti Jain
J
John C. Molina MD, MEd
S
Sophia Balderman MD
A
Abhay Singh MD, MPH
A
Aaron T. Gerds MD, MS
R
Ronald Sobecks MD
A
Anjali S. Advani MD
H
Hetty E. Carraway MD, MBA
M
Matt Kalaycio MD
S
Sudipto Mukherjee MD, PhD, MPH
DOI:10.1002/cncr.70524delete
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Abstract

Abstract

En 中文
No large, randomized trials have compared three or more tyrosine kinase inhibitors (TKIs) in a single chronic myeloid leukemia (CML) cohort. Most studies are two-arm comparisons versus imatinib, or rely on indirect methods.
Keywords:
BCR-ABL1 kinetics
chronic myeloid leukemia
event-free survival
overall survival
tyrosine kinase inhibitors
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Cancer cover
Cancer
IF:
5.1
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2.0W
Citations:
6.2W

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C
cleveland clinic lerner research institute
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15
Papers: 8
Citations: 0
C
cleveland clinic taussig cancer institute
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43
Papers: 11
Citations: 0
C
cleveland clinic
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