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Lycium ruthenicum Murray anthocyanins alleviate neuroinflammation in MPTP-induced Parkinson's disease by modulating gut microbiota and tryptophan metabolism
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DOI：10.1016/j.intimp.2026.117051.png)
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Abstract
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• Lycium ruthenicum Murray anthocyanins (LRA) mitigate neuronal degeneration in an MPTP-induced mouse model of Parkinson's disease. • LRA modulates tryptophan metabolism via gut microbiota, affecting Parkinson's disease neuroinflammation. • Supplementation with LRA enhances neuroprotection and motor function in Parkinson's disease mice. • This research elucidates the mechanisms of LRA interaction with gut microbiota for neurorestoration in Parkinson's disease.
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