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MAPK-driven glioma progression and reprogramming of the tumor-associated immune response
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DOI:10.1093/neuonc/noag147.png)
Abstract
En 中文
In brain tumors, the immunosuppressive microenvironment leads to tumor aggressiveness and immunotherapy resistance. To identify factors that regulate the glioma immune landscape, we took advantage of the disease trajectory of the MAPK-driven glioma, pleomorphic xanthoastrocytoma (PXA), which evolves from an immune-rich low-grade tumor to an aggressive glioma.
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13.4
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1.2W
Citations:
2.5W
